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K-W tests and chi-square tests were conducted using GraphPad Prism version 5 for Windows (GraphPad Inc, San Diego, CA, USA). This software is widely relied upon by scientist to analyze their data, as well as students in the field of science. Mac computers, combines GraphPad Prism v6.01 Retail. GraphPad Prism; InStat; StatMate; QuickCalcs; Data Analysis Resource Center; Company; Support; How to Buy. Please press Ctrl+F to find your cracked software you needed -I have the more latest cracked softwares. Graphpad prism 5 full version mac.
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Root Bark of Cordia millenii Essential Oil: Anti-inflammatory and Anti-nociceptive Activities
Study Design: The design of the study include collection of root bark of Cordia millenii, hydrodistillation of essential oil from the plant and evaluation of its anti-inflammatory and anti-nociceptive potentials.
Place and Duration of Study: Department of Chemistry, Lagos State University, Nigeria between May 2017 and April 2018.
Methodology: The root bark of C. millenii were collected from Ayetoro, Ilesha (7°37¢0N 4°43¢0E), Osun State, Nigeria in June 2017. Essential oils were obtained from the air-dry sample by hydrodistillation procedure in an all glass Clevenger-apparatus. The anti-inflammatory activity was evaluated by carrageenan-induced rat paw edema. The anti-nociceptive action was established from the hot-plate analysis. Statistical analysis was performed using GraphPad Prism (version 7.02).
Results: The anti-inflammatory activity of the essential oil was statistically significant (p < 0.001) at 1st and 3rd h for the 100 mg/kg p.o., at 1st-3rd h for the 200/kg mg p.o. and at 3rd and 4th h for the 400 mg/kg p.o. In addition, the 100 mg/kg p.o. showed significant activity (p < 0.01) at 2nd h. Also, the anti-inflammatory activity was significant (p < 0.05) for 100 mg/kg p.o. (4th h), 200 mg/kg p.o. (4th h) and 400 mg/kg p.o (1st h). The essential oil of C. millenii displayed high activity (p <0.001) for all doses in the hot plate anti-nociceptive assay which was time and dose independent.
Conclusion: Results demonstrate that the essential oil of C. millenii was effective in the treatment of inflammatory conditions, thereby supporting the traditional use of this herb.
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